Despite their effectiveness, steroid-induced side effects necessitate the gradual reduction of the drug as soon as the disease being treated is under control. The amount of time it takes to decrease prednisone depends on the condition being treated, the dose and duration of use, and other medical considerations. A full recovery can take anywhere from one week to several months. If you experience withdrawal symptoms from prednisone as you reduce your medication, contact your doctor immediately.
Patients who have been exposed to a cumulatively high dose of steroids or to longer exposure require a slower decline in steroids.